Douglas County – Private Non-Retail
- Charles Schwab – Financial Services (4,470 employees)
- DISH Network – Satellite TV & Equipment (2,170 employees)
- Centura Health: Parker Adventist Hospital & Castle Rock Adventist Hospital – Healthcare (1,510 employees)
- HealthONE: Sky Ridge Medical Center – Healthcare (1,360 employees)
- VISA Debit Processing Services – Financial Services (1,200 employees)
- Specialized Loan Servicing LLC – Financial Services (840 employees)
- IHS Markit – Indexed Technical Data (730 employees)
- Jacobs Engineering Group – Engineering & Architectural Services (710 employees)
- Wind Crest – Assisted Living (670 employees)
- Kaiser Permanente – Healthcare (600 employees)