Symptoms of mpox include fever, chills, swollen lymph nodes, exhaustion, muscle aches, backache, headache, sore throat, nasal congestion, cough, and rash. All people with mpox develop a rash, but not all people with mpox experience other symptoms. The rash may precede other symptoms, or the rash may appear after other symptoms begin. The rash evolves in stages, developing a scab and then healing. It may be painful or itchy. The mpox rash may appear similar to other rashes, blisters, or acne. Any person with a new rash or symptoms consistent with mpox should be evaluated by a healthcare provider.
Mpox symptoms begin within 3 weeks of exposure. Mpox is contagious for approximately 2-4 weeks. It can be spread between the period when a rash appears until the rash has completed healed and a fresh layer of skin has formed.